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What Is 2C-E Powder? A Deep Dive into the “Difficult but Worthwhile” Psychedelic
What Exactly Is 2C-E?
Buy 2C-E Powder Online. 2C-E, also known as 4-ethyl-2,5-dimethoxyphenethylamine, is a psychedelic drug of the phenethylamine and 2C families. It is taken orally.
2C-E (full name: 2,5-dimethoxy-4-ethylphenethylamine) is a synthetic psychedelic belonging to the 2C family of phenethylamines. It was first synthesized by the legendary chemist Alexander Shulgin, who documented it in his book PiHKAL (Phenethylamines I Have Known And Loved). On the street, you might hear it called “Hummingbird” or “Aquarust”.

Shulgin himself considered 2C-E one of his “magical half-dozen” — the six best psychedelic compounds he ever created. That’s high praise coming from the man who brought MDMA to the world.
But here’s the thing about 2C-E — even its inventor described it as “difficult.” In PiHKAL, he wrote: “I don’t think I like it, since it isn’t that much fun. But I intend to explore it again. There is something here that will reward the experimenter. Let it rest as being a difficult and worth-while material. A very much worth-while material”.
That quote pretty much sums up what you’ll hear from people who’ve tried it — this isn’t a party drug. It’s more like a tool for serious exploration.
2C-E Hydrochloride Powder is a potent synthetic psychedelic phenethylamine used in research for serotonergic receptor-mediated perceptual and cognitive effects.
2C-E is a synthetic psychedelic substance from the 2C family that induces powerful visual and auditory hallucinations as well as profound personal and philosophical insights.
- Light dosage: 10-15 mg
- Usual dosage: 15-25 mg
- Strong dosage: 25-40 mg
Technical Information
- Formal name: 2,5-Dimethoxy-4-ethylphenethylamine
- CAS number: 207740-23-6
- Molecular formula: C12H19NO2
- Purity: ≥98%
How It Affects You: What Users Report
The effects of 2C-E are intense and long-lasting. Most people feel it for 6 to 10 hours, with the peak lasting 3 to 6 hours. But some users report trips stretching even longer — one person described still feeling “not at baseline” a full 14 hours after dosing.
Visuals are where 2C-E really shines. Users consistently describe incredibly detailed, complex hallucinations. One person wrote about seeing “fractal machines that built the molecules of the world” when they closed their eyes. Another described walls “running as fast as a river” and carpets filled with “purple beads that looked so real, but they weren’t there”.
Dosing: Precision Is Everything
This is not a drug where you eyeball it. 2C-E is extremely dose-sensitive. A difference of just 5mg can completely change the experience.
Typical oral doses range from 10-20mg. One user who took 17mg wrote: “I’m glad I dosed very carefully, it seems that 5mg can make a huge difference in the trip. I got temperature confused easily so I will make a note to stay in a comfortable room in the future so that I don’t overheat/freeze without realizing it”.
If you snort it (insufflation), you need much less — typically under 5mg. But be warned: one 16-year-old who tried this method described it as “one of the most painful experiences of my life. It felt like razor blades slicing the inside of my nose”.
High doses can be overwhelming. One person who took around 300-400mg over a binge period described looking “like a methamphetamine addict” with “terrible acne/sores on face”.
Comparing 2C-E to Other Psychedelics
How does it stack up against more familiar substances? According to forum discussions:
– vs 2C-B: “2C-E is much more intense than 2C-B”. 2C-B is often described as a “psychedelic snack” — lighter, more visual, less mentally demanding.
– vs LSD: “This definitely isn’t anything like acid,” one user noted. Another described LSD as more “bright, positive, and visual” while 2C-E is more “dark and earthy”.
– vs Shrooms: One experienced user who had taken 40g of Colombian mushrooms said the visuals from 2C-E were beyond anything they’d experienced before.
2C-E is not a beginner’s psychedelic. It’s long, it’s intense, and it demands respect. As Shulgin said, it’s “difficult but worthwhile” — a tool for serious exploration rather than casual fun.
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